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UPDATED ADVISORY CONCERNING ELECTRONIC CIGARETTES, THE PRACTICE OF “VAPING,” “JUULING” AND USE OF OTHER ELECTRONIC NICOTINE DELIVERY SYSTEMS OR ENDS

Perinatal Hepatitis B Virus Infection

Reportable by Providers and laboratories
Perinatal Hepatitis B Virus Infection

Infectious agent:  Hepatitis B virus


Description of illness:  Hepatitis B virus (HBV) infection in a pregnant woman poses a serious risk to her infant at birth. Without post exposure prophylaxis, approximately 40% of infants born to HBV-infected mothers in the United States will develop chronic HBV infection, approximately one-fourth of whom will eventually die from chronic liver disease. Perinatal HBV transmission can be prevented by identifying HBV-infected pregnant women and providing hepatitis B immune globulin and hepatitis B vaccine to their infants within 12 hours of birth. After completion of the hepatitis B vaccine series, it is recommended that serologic testing be done at or above age 9 months to verify immunity or detect asymptomatic infection. Persons infected in infancy are typically asymptomatic until adulthood when signs and symptoms of chronic liver disease or cancer may appear.