Pseudomonas aeruginosa, Carbapenem Resistant

• None

• For laboratories able to test for carbapenemase production or carbapenemase-producing genes, report any organism with either of the following:

-Detection of carbapenemase production

-Detection of at least one carbapenemase-producing gene

• If detected via NAAT, perform culture to obtain an isolate for subsequent testing to determine the antibiotic susceptibility profile

• For laboratories unable to test for carbapenemase production or carbapenemase-producing genes, report these organisms and resistance scenarios:

-Pseudomonas aeruginosa with both of the following:

Resistant interpretation to at least one carbapenem antibiotic (excluding ertapenem) and 

Intermediate or resistant interpretation to cefepime, ceftazidime, or ceftolozane/tazobactam

• Submit isolates to TDH Division of Laboratory Services within 3 days of detection/isolation

• Specimen must be labeled with at least two unique patient identifiers and match accompanying TNDOH ARLN Lab Web Portal.

• None

• Store specimens at ambient temperature prior to shipment.

• Ship specimens at ambient temperature.
• All infectious substance shipments must conform to U.S. Department of Transportation (DOT) Hazardous Materials Regulations (HMR 49 C.F.R. Parts 171-180). 

• Only pure cultures will be accepted for testing. 
• Mixed cultures will be rejected.
• Specimens that are mislabeled will be rejected.
• Specimens that are broken in transit will be rejected.
  
• Specimens received that do not meet the specimen requirements outlined in the Directory of Services or that deviate from the special instructions will not be acceptable for testing.

• Nashville