Enterobacterales, Carbapenem Resistant
Enterobacterales, Carbapenem Resistant
| TEST NAME |
Enterobacterales - Carbapenem Resistant
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| DISEASE/DISORDER |
Carbapenem Resistant Enterobacterales |
| ALTERNATE NAME(S) |
CRE |
| METHODOLOGY |
MALDI-TOF, PCR, Antibiotic susceptibility testing, mCIM |
| SPECIAL INSTRUCTIONS |
- Isolate submission REQUIRED
- Include susceptibility test results, if available
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| ORDERING INFORMATION |
TDOH ARLN Lab Web Portal |
| Patient Preparation |
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| Specimen Collection |
- For laboratories able to test for carbapenemase production or carbapenemase-producing genes, report any organism with either of the following:
-Detection of carbapenemase production
-Detection of at least one carbapenemase-producing gene
- If detected via NAAT, perform culture to obtain an isolate for subsequent testing to determine the antibiotic susceptibility profile
- For laboratories unable to test for carbapenemase production or carbapenemase-producing genes, report these organisms and resistance scenarios:
-Enterobacterales order: Proteus species, Providencia species, and Morganella morganii with intermediate or resistant interpretations to ertapenem, meropenem, or doripenem
- All other Enterobacterales bacteria with resistant interpretation to at least one carbapenem antibiotic
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| Specimen Labeling |
- Specimen must be labeled with at least two unique patient identifiers and match the accompanying TNDOH ARLN Lab Web Portal.
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| Specimen Processing |
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| Specimen Storage and Preservation |
- Store specimens at ambient temperature until shipment.
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| Specimen Transportation |
- Ship specimens at ambient temperature.
- All infectious substance shipments must conform to U.S. Department of Transportation (DOT) Hazardous Materials Regulations (HMR 49 C.F.R. Parts 171-180).
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| Specimen Acceptability and Rejection |
- Only pure cultures will be accepted for testing.
- Mixed cultures will be rejected.
- Specimens that are mislabeled will be rejected.
- Specimens that are broken in transit will be rejected.
- Specimens received that do not meet the specimen requirements outlined in the Directory of Services or that deviate from the special instructions will not be acceptable for testing.
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| Testing Location |
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This Page Last Updated: September 15, 2025 at 2:43 PM